In Vitro Cortical Networks for Disease Modeling and Drug Evaluation
Description:
In translational research, disease models in preclinical studies are used as media for discovery of drugs or novel therapeutics. Development of in vitro models for various neurological diseases that enable efficient pharmacological or toxicological screening has been ongoing but challenging. Recognizing the potential benefit of in vitro disease models, dysfunctions in the cortical neuronal networks were induced to mimic the functional pathology of neurological symptoms using microelectrode arra…
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Date:
December 2013
Creator:
Wu, Calvin
Partner:
UNT Libraries