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 Decade: 2000-2009
 Year: 2001
 Collection: UNT Theses and Dissertations
4-Ethoxymethylphenol: a novel phytoestrogen that acts as an agonist for human estrogen receptors.

4-Ethoxymethylphenol: a novel phytoestrogen that acts as an agonist for human estrogen receptors.

Access: Use of this item is restricted to the UNT Community.
Date: December 2001
Creator: Pearce, Virginia
Description: Estrogen is the natural agonist of the estrogen receptor (ER). However, certain plant-derived compounds or phytoestrogens have been identified that mimic estrogens and act as agonists and/or antagonists of ERs, depending on subtype and target tissue. Understanding how phytoestrogens interact with ERs, and therefore effect the estrogenic response, may prove beneficial in hormone replacement therapy and in the prevention and treatment of hormone-related diseases. Using Thin Layer Chromatography, gas chromatography/mass spectrometry (GC/MS), and proton nuclear nagnetic resonance (HNMR), I identified 4-ethoxymethylphenol (4EM) found in Maclura pomifera. While most phytoestrogens are heterocyclic compounds, 4EM is a simple phenol that acts as an agonist of ER-alpha and -beta in HeLa and MCF-7 cells. To study the effect of 4EM on ER-alpha and -beta activity, I performed transient transfection assays and showed that 4EM activates ER dependent gene transcription in a dose dependent manner in both ER subtypes. Further, 4EM- mediated transcription in ER-alpha, like estrogen, was enhance in the presense of co-activators, SRC-1 (steroid receptor coactivator-1), CBP (CREB binding proteins), and E6-AP (E6-associated protein) and inhibited by trans-4- hydroxytamoxifen (4HT). I found that 4EM was specific for ER and did not activate transcription of the progesterone receptor in HeLa cells.
Contributing Partner: UNT Libraries
Accounting for human resources: Implications for theory and practice.

Accounting for human resources: Implications for theory and practice.

Date: December 2001
Creator: Stovall, Olin Scott
Description: Knowledge workers are an important resource for the typical modern business firm, yet financial reporting ignores such resources. Some researchers contend that the accounting profession has stressed reliability in order to make the accounting appear objective. Others concur, noting that accounting is an insecure profession and adopts strict rules when faced with uncertainty. Accountants have promulgated a strict rule to expense human resource costs, although many know that such resources have future benefits. Some researchers suggest that any discipline must modify its language in order to initiate change toward providing useful social ameliorations. If accounting theorists extend this idea to the accounting lexicon.s description of investments in human resources, investors and other accounting user groups might gain greater insight into how a firm fosters and nourishes human capital. I tested three hypotheses related to this issue by administering an experiment designed to assess financial analysts. perceptions about alternative financial statement treatments of human resources in an investment recommendation task. I predicted that (1) analysts' perceptions of the reliability (relevance) of the information they received would decrease (increase) as the treatment of human resources increasingly violated GAAP (became more current-oriented), (2) analysts exposed to alternative accounting treatments would report a lower ...
Contributing Partner: UNT Libraries
An analysis of sales people's perceptions of performance appraisal criteria at a telecommunications corporation.

An analysis of sales people's perceptions of performance appraisal criteria at a telecommunications corporation.

Date: December 2001
Creator: Harris, Ellen L.
Description: The purpose of this study was to identify and analyze sales people's perceptions of performance appraisal criteria in a telecommunications corporation. The study was prompted by the perceived disillusionment of the sales people with the current performance appraisal criteria. The perceptions of 67 sales people were assessed using a questionnaire developed by the researcher. One-way analysis of variance procedures (ANOVA) were used to determine if there were statistically significant differences in premise and telemarketing sales people's perceptions of performance appraisal criteria. Findings indicated that there were no statistically significant difference in premise and telemarketing sales people's perceptions of the 38 performance appraisal criteria statements. Findings did not indicate a statistically significant difference in premise and telemarketing sales people's perceptions of the performance criteria statements, the attitude or satisfaction statements, and the peripheral issue statements. Based on this study, the sales people appear to have clear perceptions of the performance appraisal criteria.
Contributing Partner: UNT Libraries
Attitudes of American and Korean early childhood educators regarding programs for gifted/talented young children.

Attitudes of American and Korean early childhood educators regarding programs for gifted/talented young children.

Date: December 2001
Creator: Song, Kyu-Woon
Description: The purpose of this research was to study the attitudes of Korean and American early childhood educators concerning gifted children and programs aimed specifically at meeting their needs. The study examined general attitudes towards giftedness and gifted education programs and factors that might affect those attitudes. The study also examined desirable environments for young gifted children. Twenty-item questionnaires were developed and logically divided into six sections (identification, teacher environment, classroom environment, parent environment, educational rights, and program). A systematic process of development, analysis, and refinement of the questionnaire was done. The questionnaires were given randomly to American educators attending the 1996 National Association for the Education of Young Children (NAEYC) conference. A random Korean sample included early childhood educators listed in the Korean Association for Early Childhood Education Directory (1995-1996) and the Korean Association for Child Care Directory (1995-1996). All subjects were members of one of three groups: (a) teacher educators, (b) teachers, and (c) administrators/directors. The surveys found agreement between Korean and American early childhood educators on the importance of knowing the strengths of individual gifted children, the need to stimulate higher order thinking skills, the rights of gifted children to an appropriate education, a perception of more work ...
Contributing Partner: UNT Libraries
Borel Determinacy and Metamathematics

Borel Determinacy and Metamathematics

Date: December 2001
Creator: Bryant, Ross
Description: Borel determinacy states that if G(T;X) is a game and X is Borel, then G(T;X) is determined. Proved by Martin in 1975, Borel determinacy is a theorem of ZFC set theory, and is, in fact, the best determinacy result in ZFC. However, the proof uses sets of high set theoretic type (N1 many power sets of ω). Friedman proved in 1971 that these sets are necessary by showing that the Axiom of Replacement is necessary for any proof of Borel Determinacy. To prove this, Friedman produces a model of ZC and a Borel set of Turing degrees that neither contains nor omits a cone; so by another theorem of Martin, Borel Determinacy is not a theorem of ZC. This paper contains three main sections: Martin's proof of Borel Determinacy; a simpler example of Friedman's result, namely, (in ZFC) a coanalytic set of Turing degrees that neither contains nor omits a cone; and finally, the Friedman result.
Contributing Partner: UNT Libraries
The characteristics of teacher-directed modeling evidenced in the practices of three experienced high school choral directors.

The characteristics of teacher-directed modeling evidenced in the practices of three experienced high school choral directors.

Date: December 2001
Creator: Grimland, Fredna H.
Description: The purpose of this study was to analyze the characteristics of teacher directed modeling evidenced in the practices of three experienced high school choral directors. Research questions were: 1. What modeling activities were exhibited in each teacher's rehearsals? 2. When viewing a 45-minute composite tape of each teacher's instructional activities representative of all rehearsals, what instructional behaviors did each choral director recognize and identify as modeling? 3. What instructional episodes on the composite tape not identified by the teachers contained elements of modeling? 4. What other episodes from the remainder of each choral director's rehearsal practice contributed to an understanding of modeling? Videotapes of three high school choral directors were recorded over the course of one semester. Excerpts from rehearsals were combined to form a 45-minute composite tape of each choral director. A text transcription was made of the composite tape. Participant directors viewed their tape and identified instructional episodes that they recognized as examples of modeling. Identifications were analyzed, and descriptive categories of modeling behaviors were established. Modeling was found to be a teacher generated or delegated act of demonstration. Demonstrations were musical or non-musical and belonging to either of three distinct categories: audible, visible, or process modeling. Subdivisions ...
Contributing Partner: UNT Libraries
Characterization of  Moraxella bovis Aspartate Transcarbamoylase

Characterization of Moraxella bovis Aspartate Transcarbamoylase

Access: Use of this item is restricted to the UNT Community.
Date: December 2001
Creator: Hooshdaran, Sahar
Description: Aspartate transcarbamoylase (ATCase) catalyzes the first committed step in the pyrimidine biosynthetic pathway. Bacterial ATCases have been divided into three classes, class A, B, and C, based on their molecular weight, holoenzyme architecture, and enzyme kinetics. Moraxella bovis is a fastidious organism, the etiologic agent of infectious bovine keratoconjunctivitis (IBK). The M. bovis ATCase was purified and characterized for the first time. It is a class A enzyme with a molecular mass of 480 to 520 kDa. It has a pH optimum of 9.5 and is stable at high temperatures. The ATCase holoenzyme is inhibited by CTP > ATP > UTP. The Km for aspartate is 1.8 mM and the Vmax 1.04 µmol per min, where the Km for carbamoylphosphate is 1.05 mM and the Vmax 1.74 µmol per min.
Contributing Partner: UNT Libraries
Characterization of the aspartate transcarbamoylase (ATC2) that is found in the pyrBC’ complex of  Bordetella pertussis

Characterization of the aspartate transcarbamoylase (ATC2) that is found in the pyrBC’ complex of Bordetella pertussis

Date: December 2001
Creator: Dill, Michael T
Description: An aspartate transcarbamoylase (ATCase) gene from Bordetella pertussis was amplified by PCR and ligated into pT-ADV for expression in Escherichia coli. This particular ATCase (pyrB) was an inactive gene found adjacent to an inactive dihydroorotase (DHOase) gene (pyrC'). This experiment was undertaken to determine whether this pyrB gene was capable of expression alone or if it was capable of expression only when cotransformed with a functional pyrC'. When transformed into E. coli TB2 pyrB-, the gene did not produce any ATCase activity. The gene was then co-transformed into E. coli TB2 pyrB- along with a plasmid containing the pyrC' gene from Pseudomonas aeruginosa and assayed for ATCase activity. Negative results were again recorded.
Contributing Partner: UNT Libraries
Characterizaton of Triethoxyfluorosilane and Tetraethoxysilane Based Aerogels

Characterizaton of Triethoxyfluorosilane and Tetraethoxysilane Based Aerogels

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Date: December 2001
Creator: Roepsch, Jodi Ann
Description: Aerogels are highly porous, low dielectric constant (low k) materials being considered by the semiconductor industry as an interlayer dielectric. Low k materials are needed to overcome capacitance problems that limit device feature sizes. Precursors triethoxyfluorosilane (TEFS) and tetraethoxysilane (TEOS) were used to prepare bulk aerogels. Samples were prepared by sol-gel methods, and then carbon dioxide supercritically-dried. Effects of varying the water to precursor ratio were studied with respect to aerogel properties and microstructure. Methods of analysis for this study include FTIR-ATR, TEM, RBS, EDS, SEM, dielectric constant determination by impedance and surface area by gas adsorption. Si-F bonds were determined to be present in both acid- and base-catalyzed TEFS as well as HF-catalyzed TEOS. Fluorine promotes a fractal network microstructure as opposed to a particle-like microstructure. Surface area and dielectric constant were determined to increase slightly with increases in the water to precursor ratio.
Contributing Partner: UNT Libraries
Combat Reconsidered: A Statistical Analysis of Small-Unit Actions During the American Civil War

Combat Reconsidered: A Statistical Analysis of Small-Unit Actions During the American Civil War

Date: December 2001
Creator: Barloon, Mark C
Description: Historians often emphasize the physical features of battleterrain, weaponry, troop formations, earthworks, etc.in assessments of Civil War combat. Most scholars agree that these external combat conditions strongly influenced battle performance. Other historians accentuate the ways in which the mental stresses of soldiering affected combat performance. These scholars tend to agree that fighting effectiveness was influenced by such non-physical combat conditions as unit cohesion, leadership, morale, and emotional stress. Few authors argue that combat's mental influences were more significant in determining success or failure than the physical features of the battlefield. Statistical analysis of the 465 tactical engagements fought by twenty-seven Federal regiments in the First Division of the Army of the Potomac's Second Corps throughout the American Civil War suggests that the mental aspects of battle affected fighting efficiency at least as muchand probably more thancombat's physical characteristics. In other words, the soldiers' attitudes, opinions, and emotions had a somewhat stronger impact on combat performance than their actions, positions, and weaponry.
Contributing Partner: UNT Libraries
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