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An Application of the Reformatsky Reaction to the Thiophene Series of Compounds

Description: In view of the increasing importance of thiophene derivatives as chemotherapeutic agents, it was considered of interest to apply the Reformatsky reaction to the synthesis of compounds containing the thiophene nucleus with the thought that these might serve as intermediates for further syntheses.
Date: 1949
Creator: Hicks, Howard A.
Partner: UNT Libraries
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Hydantoin Derivatives as Anticonvulsants. I. 5-Cyclohexylalkyl-5-(2-Thienyl)Hydantoins

Description: The study herein described represents a continuation of the work on 5-(2-thienyl)-5-substituted hydantoins which has been in progress in the laboratories of the North Texas State College for the past several years. It has for its purpose the study of the effect of lengthening the carbon chain connecting a cyclohexyl radical to 5-(2-thienyl)hydantoin in the 5- position.
Date: 1949
Creator: Baker, Andy Albert
Partner: UNT Libraries
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The Syntheses of Amino Substituted Salicylic Acids and Related Compounds

Description: The introduction of the ether linkage into various compounds imparts physiological activity, hence the synthesis of various ether derivatives involving the phenol group seemed to be a possible route to tuberculostatic substances. The compounds reported in this work are to be tested for tuberculostatic properties by Parke, Davis and Company.
Date: 1949
Creator: Gerber, Martin
Partner: UNT Libraries
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A-(Substitutedbenzenesulfonyl)-Substitutedacetophenones

Description: This thesis discusses the preparation of a-(o-nitro-p-methylphenylmercapto)-acetophenone by the reaction between acetophenone and o-nitro-p-methylbenzenesulfenyl chloride in boiling chloroform. The use of stannous chloride in glacial acetic acid for the reduction of nitro groups to amino groups was found generally satisfactory in spite of the difficulty often met with in isolating the amino product.
Date: 1948
Creator: Thomas, John Wylie
Partner: UNT Libraries
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The Synthesis and Testing of Differential Herbicides

Description: This investigation was limited to the preparation of substituted phenoxyacetic acids and related compounds. The types of substances prepared for testing can, in general, be placed in three groups. These are: aryloxyacetic acids, arylmercaptoacetic acids, and those acids containing the thiophene nucleus.
Date: 1948
Creator: Ashmore, James
Partner: UNT Libraries
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The Mercury-Sensitized Photo-Reactions of 2,3-Dimethyl Butane

Description: The work encompassed by this thesis is partially a reproduction of the results obtained by John A. Marcia in his work on the photo-chemical reactions of branched hydrocarbons. The previous work done on this particular problem was rendered partially valueless because of the loss of the liquid hydrocarbon product when a fractionation column at the Texas Company Laboratory, Beacon, New York, broke during the fractionation run.
Date: 1947
Creator: Sutton, Cecil C.
Partner: UNT Libraries
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A Study of Sympathiomimetic Amines, Synthesis of O-Alkylhydroxylamines

Description: Although many sympathomimetic amines have been prepared, the perfect one has not yet been made. Chemists are still attempting to synthesize a selective drug with more prolonged effects and free from side reactions or compensatory vasodilation. With this idea in mind it seemed feasible to prepare a group of O-substituted hydroxylamines.
Date: 1947
Creator: Robbins, Margaret C.
Partner: UNT Libraries
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The Synthesis of Certain Alkyl Alpha-(2-Dialkylam Inoalkoxy)Phenylacetates

Description: This thesis describes the procedures used in preparation of the derivatives of certain alkyl phenylacetates and the necessary intermediate compounds. Compounds resembling the structure of Benadryl were prepared in this study in the hope that at least one might prove to be of value in the fight against allergy.
Date: 1947
Creator: Mark, Roscoe Dewey
Partner: UNT Libraries
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Thiophene Analogs of DDT; O-Alkylhydorxylamine Hydrochorides; Dialkylaminoalkyl Esters of Phenoxyacetic Acid

Description: This thesis describes three separate and unrelated chemical experiments. The first investigates analogs for the compound DDT. The second investigates the properties of O-substituted hydroxylamines. The third investigates the action of slight changes to the structure of an antihistaminic agent.
Date: 1947
Creator: Mattison, Marjorie Bess
Partner: UNT Libraries
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