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 Degree Level: Master's
 Collection: UNT Theses and Dissertations
In Vitro Investigations of Antibiotic Influences on Nerve Cell Network Responses to Pharmacological Agents

In Vitro Investigations of Antibiotic Influences on Nerve Cell Network Responses to Pharmacological Agents

Date: December 2014
Creator: Sawant, Meera
Description: Neuronal networks, derived from mouse embryonic frontal cortex (FC) tissue grown on microelectrode arrays, were used to investigate effects of gentamicin pretreatment on pharmacological response to the L-type calcium channel blocker, verapamil. Gentamicin is a broad spectrum antibiotic used to control bacterial contamination in cell culture. The addition of gentamicin directly to medium affects the pharmacological and morphological properties of the cells in culture. A reproducible dose response curve to verapamil from untreated cultures was established and the mean EC50 was calculated to be 1.5 ± 0.5 μM (n=10). 40 μM bicuculline was added to some cell cultures to stabilize activity and verapamil dose response curves were performed in presence of bicuculline, EC50 1.4 ± 0.1 μM (n=9). Statistical analysis showed no significant difference in verapamil EC50s values obtained in presence of bicuculline and hence the data was combined and a standard verapamil EC50 was calculated as 1.4 ± 0.13 μM (n=19). This EC50 was then used to compare verapamil EC50s obtained from neuronal cell cultures with chronic and acute exposures to gentamicin. FC cultures (21- 38 days old) were found to be stable in presence of 2300 μM gentamicin. The recommended concentration of gentamicin for contamination control is 5uL ...
Contributing Partner: UNT Libraries
Electromagnetic Shielding Properties of Iron Oxide Impregnated Kenaf Bast Fiberboard

Electromagnetic Shielding Properties of Iron Oxide Impregnated Kenaf Bast Fiberboard

Date: December 2014
Creator: Ding, Zhiguang
Description: The electromagnetic shielding effectiveness of kenaf bast fiber based composites with different iron oxide impregnation levels was investigated. The kenaf fibers were retted to remove the lignin and extractives from the pores in fibers, and then magnetized. Using the unsaturated polyester and the magnetized fibers, kenaf fiber based composites were manufactured by compression molding process. The transmission energies of the composites were characterized when the composite samples were exposed under the irradiation of electromagnetic (EM) wave with a changing frequency from 9 GHz to 11 GHz. Using the scanning electron microscope (SEM), the iron oxide nanoparticles were observed on the surfaces and inside the micropore structures of single fibers. The SEM images revealed that the composite’s EM shielding effectiveness was increased due to the adhesion of the iron oxide crystals to the kenaf fiber surfaces. As the Fe content increased from 0% to 6.8%, 15.9% and 18.0%, the total surface free energy of kenaf fibers with magnetizing treat increased from 44.77 mJ/m2 to 46.07 mJ/m2, 48.78 mJ/m2 and 53.02 mJ/m2, respectively, while the modulus of elasticity (MOE) reduced from 2,875 MPa to 2,729 MPa, 2,487 MPa and 2,007 MPa, respectively. Meanwhile, the shielding effectiveness was increased from 30-50% to 60-70%, ...
Contributing Partner: UNT Libraries
The Effects of Model Prompts on Joint Attention Initiations in Children with Autism

The Effects of Model Prompts on Joint Attention Initiations in Children with Autism

Date: December 2014
Creator: James-Kelly, Kimberly L
Description: The general purpose of the current study was to evaluate the effects of minimally intrusive prompting procedures and preferred stimuli on protodeclarative joint attention initiations in children diagnosed with autism spectrum disorder (ASD). Two boys and one girl diagnosed with ASD participated. The experimenter provided attention and social interaction following protodeclarative initiations throughout all phases of the study. During intervention, a model prompt was delivered every 30 s if the participant failed to initiate a bid for joint attention. Results for the first participant show that a model prompt was sufficient to increase the rate of protodeclarative initiations across stimulus sets. Generalization was seen across sets, but not across environments. Subsequently, the model prompt was sufficient to increase the rate of protodeclarative initiations across sets in a second setting (classroom). Results for the second participant are inconclusive. Data collected during the initial baseline condition show that she engaged in an incompatible verbal response across sets. When pictorial stimuli depicting highinterest items and activities were introduced, the rate of protodeclarative initiations increased over time. We then returned to original baseline condition and saw an initial decrease, followed by a steady increase in the rate of protodeclarative initiations. The third participant withdrew ...
Contributing Partner: UNT Libraries
Cowboys, “Queers,” and Community: the Aids Crisis in Houston and Dallas, 1981-1996

Cowboys, “Queers,” and Community: the Aids Crisis in Houston and Dallas, 1981-1996

Date: August 2014
Creator: Bundschuh, Molly Ellen
Description: This thesis examines the response to the AIDS crisis in Houston and Dallas, two cities in Texas with the most established gay communities highest number of AIDS incidences. Devoting particular attention to the struggles of the Texas’ gay men, this work analyzes the roadblocks to equal and compassionate care for AIDS, including access to affordable treatment, medical insurance, and the closure of the nation’s first AIDS hospital. In addition, this thesis describes the ways in which the peculiar nature of AIDS as an illness transformed the public perception of sickness and infection. This work contributes to the growing study of gay and lesbian history by exploring the transformative effects of AIDS on the gay community in Texas, a location often forgotten within the context of the AIDS epidemic.
Contributing Partner: UNT Libraries
The Power of Perception: Women and Politics at the Early Georgian Court

The Power of Perception: Women and Politics at the Early Georgian Court

Date: August 2014
Creator: Stewart, Hailey A.
Description: The early Georgian period illustrates how the familial dynamic at court affected women’s opportunity to exert political influence. The court represented an important venue that allowed women to declare a political affiliation and to participate in political issues that suited their interests. Appearances often at variance with reality allowed women to manipulate and test their political abilities in order to have the capability to exercise any possible power. Moreover, some women developed political alliances and relationships that supported their own interests. The family structure of the royal household affected how much influence women had. The perception of holding power permitted certain women to behave politically. This thesis will demonstrate that the distinction between appearances and reality becomes vital in assessing women at the early Georgian court by examining some women’s experiences at court during the reigns of the first two Georges. In some cases, the perceived power of a courtier had a real basis, and in other instances, it gave them an opportunity to assess the extent of their political power. Women’s political participation has been underestimated during the early Georgian period, while well-documented post-1760.
Contributing Partner: UNT Libraries
Glass Forming Ability, Magnetic Properties, and Mechanical Behavior of Iron-Based and Cobalt-Based Metallic Glasses

Glass Forming Ability, Magnetic Properties, and Mechanical Behavior of Iron-Based and Cobalt-Based Metallic Glasses

Date: December 2014
Creator: Veligatla, Medha
Description: Lack of crystalline order and microstructural features such as grain/grain-boundary in metallic glasses results in a suite of remarkable attributes including very high strength, close to theoretical elasticity, high corrosion and wear resistance, and soft magnetic properties. In particular, low coercivity and high permeability of iron and cobalt based metallic glass compositions could potentially lead to extensive commercial use as magnetic heads, transformer cores, circuits and magnetic shields. In the current study, few metallic glass compositions were synthesized by systematically varying the iron and cobalt content. Thermal analysis was done and included the measurement of glass transition temperature, crystallization temperature, and the enthalpies of relaxation and crystallization. Magnetic properties of the alloys were determined including saturation magnetization, coercivity, and Curie temperature. The coercivity was found to decrease and the saturation magnetization was found to increase with the increase in iron content. The trend in thermal stability, thermodynamic properties, and magnetic properties was explained by atomic interactions between the ferromagnetic metals and the metalloids atoms in the amorphous alloys. Mechanical behavior of iron based metallic glasses was evaluated in bulk form as well as in the form of coatings. Iron based amorphous powder was subjected to high power mechanical milling and ...
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The Role of the Actin Cytoskeleton in Asymmetric Cell Division in Maize

The Role of the Actin Cytoskeleton in Asymmetric Cell Division in Maize

Date: August 2014
Creator: Alhassan, Hassan Hamdan
Description: Stomata are specialized plant structures required for gaseous exchange with the outer environment. During stomata formation, the cytoskeleton plays an important role in controlling the division of the individual cells leading to the generation of the stomata complex. Two mutants that affect microfilament and microtubule organization in subsidiary mother cells include brk1 and dcd1. While only 20% of the subsidiary cells in the brk1 and dcd1 single mutants are abnormally shaped, it was reported that there is a synergistic effect between the brk1 and dcd1 mutations in the brk1; dcd1 double mutant since 100% of the subsidiary cells are abnormal. The focus of this research is to try to understand this synergistic effect by investigating the actin cytoskeleton and nuclear position in the single and double mutants. The reported results include the observation that the size of actin patch was largest in the wild-type subsidiary mother cells (SMCs) and smallest in dcd1 and brk1; dcd1 SMCs and that brk1 and brk1; dcd1 double mutants had fewer actin patches than wild-type and dcd1 SMCs. Additionally, we observed that some SMCs that did not have actin patches still underwent nuclear migration suggesting that nuclear migration may not be solely dependent on actin ...
Contributing Partner: UNT Libraries
Evidence for Multiple Functions of a Medicago Truncatula Transporter

Evidence for Multiple Functions of a Medicago Truncatula Transporter

Access: Use of this item is restricted to the UNT Community.
Date: December 2014
Creator: Huang, Ying-Sheng
Description: Legumes play an important role in agriculture as major food sources for humans and as feed for animals. Bioavailable nitrogen is a limiting nutrient for crop growth. Legumes are important because they can form a symbiotic relationship with soil bacteria called rhizobia that results in nitrogen-fixing root nodules. In this symbiosis, rhizobia provide nitrogen to the legumes and the legumes provide carbon sources to the rhizobia. The Medicago truncatula NPF1.7/NIP/LATD gene is essential for root nodule development and also for proper development of root architecture. Work in our lab on the MtNPF1.7/MtNIP/LATD gene has established that it encodes a nitrate transporter and strongly suggests it has another function. Mtnip-1/latd mutants have pleiotropic defects, which are only partially explained by defects in nitrate transport. MtNPF1.7/NIP/LATD is a member of the large and diverse NPF/NRT1(PTR) transporter family. NPF/NRT1(PTR) members have been shown to transport other compounds in addition to nitrate: nitrite, amino acids, di- and tri-peptides, dicarboxylates, auxin, abscisic acid and glucosinolates. In Arabidopsis thaliana, the AtNPF6.3/NRT1.1( CHL1) transporter was shown to transport auxin as well as nitrate. Atchl1 mutants have defects in root architecture, which may be explained by defects in auxin transport and/or nitrate sensing. Considering the pleiotropic phenotypes observed ...
Contributing Partner: UNT Libraries
An Assessment of a Hospice and Palliative Care Partnership Program

An Assessment of a Hospice and Palliative Care Partnership Program

Date: December 2014
Creator: Munene, Grace N
Description: This project attempts to describe how a hospice and palliative care partnership program works. Through the assessment of one such program, the researcher sought to find out the essential components of the partnership including how the two partner organizations interact and work together. Data was collected using various methods: document review of organization documents such as newsletters, annual or quarterly reports, brochures and other available literature e.g. materials on organizations’ website and on social media; in-depth interviews with stakeholders of both organizations that included staff and board members; observation of staff working; and participant observation during organization events. The findings of the research shows that in order for organizations to have an effective partnership program in place, both partners need to have strong leadership in place, possess a willingness to learn from each other, maintain regular communication, and visit each other regularly. With this in place, several outcomes of the program are likely such as: increasing advocacy for hospice and palliative care, increasing visibility of the organizations both nationally and internationally, and provides an opportunity for organizations to network with other organizations in their locality in order to achieve partnership objectives. The study further reveals that global collaborations in the ...
Contributing Partner: UNT Libraries
Evaluation of Program Effectiveness: a Look at the Bedford Police Department’s Strategy Towards Repeat Victimization in Domestic Violence and Mental Health

Evaluation of Program Effectiveness: a Look at the Bedford Police Department’s Strategy Towards Repeat Victimization in Domestic Violence and Mental Health

Date: August 2014
Creator: Huskey, Michael G.
Description: The primary goal of this study was to evaluate the effectiveness of a program being run by the Bedford Police Department’s Repeat Victimization Unit on domestic violence and mental health and mental retardation. The study sought to determine whether the program was effective in reducing instances of repeat victimization in domestic violence and MHMR victims. Additionally the program investigated whether or not the program was effective at reducing victimization severity, and which demographic could be identified as the most victimized. Participants consisted of 157 domestic violence and MHMR victims in the city of Bedford, Tx between November 11, 2012 to July 30, 2013. Findings indicate that levels of repeat victimization for domestic violence and MHMR are relatively low regardless of whether the victim received services through the repeat victimization program or not. Additionally the severity of these repeat victimizations remains relatively constant regardless of whether services were received through the program or not. Implications and findings are discussed.
Contributing Partner: UNT Libraries
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