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  Partner: UNT Libraries
 Degree Discipline: Chemistry
 Collection: UNT Theses and Dissertations
Barbituric Acids as Anticonvulsants.  IV.  5-Substituted-Mercapto Derivatives of 5-Phenylbarbituric Acids.

Barbituric Acids as Anticonvulsants. IV. 5-Substituted-Mercapto Derivatives of 5-Phenylbarbituric Acids.

Date: 1951
Creator: Shahan, Howard Wayne
Description: This study involves compounds of the barbituric acid series are well known for their use as anesthetics and sedatives.
Contributing Partner: UNT Libraries
Barbituric Acids. VI. 5-substituted-mercapto Derivatives of 5-ethylbarbituric Acid

Barbituric Acids. VI. 5-substituted-mercapto Derivatives of 5-ethylbarbituric Acid

Date: June 1954
Creator: Jeanes, Cecil Byron
Description: The reaction of 5-bromo-5-ethylbarbituric acid with mercaptan and pyridine in cold ether solution was studied and was found to be satisfactory for the preparation of the compounds reported in this work.
Contributing Partner: UNT Libraries
Barbituric Acids.  VII.  5-alkyl-derivatives of 5-ethoxy-barbituric Acid

Barbituric Acids. VII. 5-alkyl-derivatives of 5-ethoxy-barbituric Acid

Date: January 1955
Creator: Hyde, Harold Wayne
Description: A great deal of research has been devoted in recent years to the search for new drugs for the treatment of epilepsy and related convulsive disorders. This emphasis is occasioned by the fact that no one drug is effective for all patients, and also by the fact that the toxicity of a drug varies considerably from one patient to another. Among the most effective drugs are certain members of the hydantoin and barbituric acid series. For some time there has been in progress in this laboratory an investigation of members of these two series in which a hetro atom attached directly to the hetrocyclic nucleus is introduced into the side chain at position five of these two series.
Contributing Partner: UNT Libraries
Barbituric Acids. VIII. 5-substituted-5-(1-pyrrolidyl)barbituric Acids

Barbituric Acids. VIII. 5-substituted-5-(1-pyrrolidyl)barbituric Acids

Date: 1957
Creator: Compton, Ross Davis
Description: The purpose of this investigation then was the preparation of a series of 5-substituted-5-(1-pyrrolidyl)barbituric acids in which R would consist of alkyl groups ranging in size from methyl to amyl, and other groups such as phenyl and benzyl. These compounds are to be tested elsewhere for hypnotic and anticonvulsant activity.
Contributing Partner: UNT Libraries
Barbituric Acids.  V.  5-substituted-mercapto Derivatives of 5-isoamylbarbituric Acid

Barbituric Acids. V. 5-substituted-mercapto Derivatives of 5-isoamylbarbituric Acid

Date: August 1952
Creator: Peterson, Paul Eugene
Description: Since no mention has been found in the literature of any 5-substituted mercapto-5-alkyl derivatives of barbituric acid, it was thought to be of interest to prepare a series of compounds containing sulfur attached directly to the barbituric acid nucleus. 5-substituted mercapto-5-isoamylbarbituric acids were chosen as representative of barbituric acids in which the alkyl group has a fairly high molecular weight.
Contributing Partner: UNT Libraries
Base Effects on the Thermal Decomposition of Sec-butyllithium Solutions

Base Effects on the Thermal Decomposition of Sec-butyllithium Solutions

Date: June 1966
Creator: Adams, George Michael
Description: The pyrolysis of sec-butyllithium in solution was studied in an attempt to understand the loss of stereo-specificity and the atypical kinetics that have been reported. Additionally, the effect of added lithium alkoxides was studied to determine their effects on the highly reactive sec-butyllithium substrate.
Contributing Partner: UNT Libraries
Biological Inhibitors

Biological Inhibitors

Date: December 1971
Creator: Sargent, Dale Roger
Description: Four isosteric series of plant growth-regulating compounds were prepared. Using an Avena sativa coleptile assay system, derivatives in series I and IV inhibited segment elongation to a greater degree than did comparable derivatives in series II and III.
Contributing Partner: UNT Libraries
Bis Ammonium Salts of Dialkylaminoalkoxypropionitriles

Bis Ammonium Salts of Dialkylaminoalkoxypropionitriles

Date: August 1957
Creator: Woods, Roy Jack
Description: This paper concerns the preparation of some bis derivatives of dialkylaminoalkoxypropionitirles from trimethylene, hexamethylene, octomethylene, and decamethylene bromides. These compounds are to be tested for curariform activity and anesthetic values by Parke, Davis and Company.
Contributing Partner: UNT Libraries
Bonding Studies in Group IV Substituted n,n-dimethylanilines

Bonding Studies in Group IV Substituted n,n-dimethylanilines

Date: December 1971
Creator: Drews, Michael James
Description: The purpose of the present work is to study the effects of the trimethylsilyl and trimethylgermyl substituents on the N,N-dimethylamino ring system. Both ground and excited state interactions were studied and their magnitudes determined. The experimental data were then used in conjunction with molecular orbital calculations to differentiate among, and determine the importance of, d-p bonding, hyperconjugation or polarization of the trimethylsilyl group on the ground and excited state bonding.
Contributing Partner: UNT Libraries
Bonding Studies on Organolithium Compounds

Bonding Studies on Organolithium Compounds

Date: August 1968
Creator: Peyton, Gary
Description: This study is concerned with the nature of the relatively unusual bonding which occurs in organolithium compounds as a direct result of the oligomerization and possible explanations for that bonding.
Contributing Partner: UNT Libraries