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 Collection: UNT Theses and Dissertations
4-Ethoxymethylphenol: a novel phytoestrogen that acts as an agonist for human estrogen receptors.

4-Ethoxymethylphenol: a novel phytoestrogen that acts as an agonist for human estrogen receptors.

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Date: December 2001
Creator: Pearce, Virginia
Description: Estrogen is the natural agonist of the estrogen receptor (ER). However, certain plant-derived compounds or phytoestrogens have been identified that mimic estrogens and act as agonists and/or antagonists of ERs, depending on subtype and target tissue. Understanding how phytoestrogens interact with ERs, and therefore effect the estrogenic response, may prove beneficial in hormone replacement therapy and in the prevention and treatment of hormone-related diseases. Using Thin Layer Chromatography, gas chromatography/mass spectrometry (GC/MS), and proton nuclear nagnetic resonance (HNMR), I identified 4-ethoxymethylphenol (4EM) found in Maclura pomifera. While most phytoestrogens are heterocyclic compounds, 4EM is a simple phenol that acts as an agonist of ER-alpha and -beta in HeLa and MCF-7 cells. To study the effect of 4EM on ER-alpha and -beta activity, I performed transient transfection assays and showed that 4EM activates ER dependent gene transcription in a dose dependent manner in both ER subtypes. Further, 4EM- mediated transcription in ER-alpha, like estrogen, was enhance in the presense of co-activators, SRC-1 (steroid receptor coactivator-1), CBP (CREB binding proteins), and E6-AP (E6-associated protein) and inhibited by trans-4- hydroxytamoxifen (4HT). I found that 4EM was specific for ER and did not activate transcription of the progesterone receptor in HeLa cells.
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9-Lipoxygenase Oxylipin Pathway in Plant Response to Biotic Stress

9-Lipoxygenase Oxylipin Pathway in Plant Response to Biotic Stress

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Date: May 2012
Creator: Nalam, Vamsi J.
Description: The activity of plant 9-lipoxygenases (LOXs) influences the outcome of Arabidopsis thaliana interaction with pathogen and insects. Evidence provided here indicates that in Arabidopsis, 9-LOXs facilitate infestation by Myzus persicae, commonly known as the green peach aphid (GPA), a sap-sucking insect, and infection by the fungal pathogen Fusarium graminearum. in comparison to the wild-type plant, lox5 mutants, which are deficient in a 9-lipoxygenase, GPA population was smaller and the insect spent less time feeding from sieve elements and xylem, thus resulting in reduced water content and fecundity of GPA. LOX5 expression is induced rapidly in roots of GPA-infested plants. This increase in LOX5 expression is paralleled by an increase in LOX5-synthesized oxylipins in the root and petiole exudates of GPA-infested plants. Micrografting experiments demonstrated that GPA population size was smaller on plants in which the roots were of the lox5 mutant genotype. Exogenous treatment of lox5 mutant roots with 9-hydroxyoctadecanoic acid restored water content and population size of GPA on lox5 mutants. Together, these results suggest that LOX5 genotype in roots is critical for facilitating insect infestation of Arabidopsis. in Arabidopsis, 9-LOX function is also required for facilitating infection by F. graminearum, which is a leading cause of Fusarium head ...
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Academic Dishonesty:  Attitudes and Behaviors of Fundamentalist Christian College Students

Academic Dishonesty: Attitudes and Behaviors of Fundamentalist Christian College Students

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Date: December 2000
Creator: Sunday, William G.
Description: This study was designed to examine: (1) the extent to which cheating occurs in fundamentalist Christian colleges; (2) the attitudes of fundamentalist Christian college students toward cheating; (3) attitudes of fundamentalist Christian college students toward cheating among their peers; (4) the kinds of cheating practices of fundamentalist Christian college students; (5) the degree to which students engage in neutralizing behavior to justify cheating; (6) differences in cheating behaviors according to gender; (7) differences in cheating behaviors according to ethnicity; and (8) differences in cheating behaviors according to the length of duration of Christian commitment. Based upon the responses of 337 students attending 3 different Christian colleges, it was concluded that: (1) most Christian fundamentalist students do not engage in cheating; (2) respondents believe that each of 17 self-reported cheating behaviors are serious forms of cheating; (3) respondents are unlikely to report cheating among peers; (4) plagiarism is the most common cheating behavior; (5) most respondents justify cheating on the basis of the workload at school and the pressure to obtain good grades; (6) there are no differences in cheating behavior according to gender; (7) there are differences in cheating behavior according to groups; and (8) most respondents do not cheat ...
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Accuracy of Self-Reported Height, Weight, and Calculated BMI and Resulting FITNESSGRAM® Healthy Fitness Zone Classification

Accuracy of Self-Reported Height, Weight, and Calculated BMI and Resulting FITNESSGRAM® Healthy Fitness Zone Classification

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Date: May 2006
Creator: Rowell, Chelsie Joyce
Description: The determination of adiposity in adolescents is often assessed with calculations of body mass indices (BMI). Researchers often obtain these measurements from self-reported (SR) values. The purpose of this study was to determine the accuracy of SR height, weight, and calculated BMI (from height and weight). SR and actual measured (ME) BMI values were compared with standards from the FITNESSGRAM® Healthy Fitness Zone (HFZ) classifications. SR height and calculated BMI were found to be accurate while SR weight was, on average, underreported by 4.77 lbs. Because of these errors in SR height and weight, accuracy of classification into the FITNESSGRAM® HFZ was compromised. Consequently, it is important that researchers ascertain actual values of height and weight when measuring adolescents rather than use those from self-reports.
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Accuracy variations in human facial identification based on time of exposure.

Accuracy variations in human facial identification based on time of exposure.

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Date: December 2006
Creator: Cowle, Kenneth M.
Description: This study examined the relationship between time of exposure to the human face and accurate subsequent photo line-up identification. A volunteer group of 124 undergraduate students was divided into three approximately equal sized subgroups. The three groups were then exposed to a video or a portion of a video depicting a theft. Exposure times ranged from two minutes to 30 seconds. The subjects were then given a questionnaire and shown a photo line-up of the mock perpetrator and five foils. Subjects were asked to identify the perpetrator and mark that identification on the questionnaire. Results of the experiment indicated that the longer a subject was exposed the greater the possibility of an accurate identification.
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Adherence and haemagglutination of  Moraxella catarrhalis.

Adherence and haemagglutination of Moraxella catarrhalis.

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Date: August 2000
Creator: Kosterman, Edward, III
Description: M. catarrhalis is a gram-negative diplococci frequently associated with infections of the upper respiratory tract. During the past decade, some preliminary studies have attempted to elucidate mechanisms of adherence and haemagglutination of M. catarrhalis. These studies have reported, in many cases, inconsistent results. There are two purposes of this research. First, identify mechanisms that may potentially be associated with the adherence and haemagglutination of M. catarrhalis. Second, suggest research directions that may be fruitful in clarifying these mechanisms.
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Adolescent Insomnia as a Predictor of Early Adulthood Outcomes

Adolescent Insomnia as a Predictor of Early Adulthood Outcomes

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Date: December 2006
Creator: Roane, Brandy Michelle
Description: Recent research found insomnia is a risk factor for psychiatric disorders in adults. To see if the same would be true in adolescents, the current study re-analyzed data from a national longitudinal study collected by ADDHealth that evaluated health behaviors in 4552 adolescents (mean age 14.9 years [SD 1.7]) at baseline and again 7-8 years later (n = 3489) during young adulthood. Insomnia was reported by 9.2% of the adolescents. Cross-sectionally, adolescent insomnia was associated with alcohol, cannabis, non-cannabis drugs, and tobacco use, and depression after controlling for gender and ethnicity. Prospectively, adolescent insomnia was a significant risk factor for depression diagnosis, suicidal ideation, and the use of depression and stress prescription medications in young adulthood after controlling for gender, ethnicity, and significant baseline variable. In addition, a trend was noted for suicidal attempts.
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African Refugee Parents' Involvement in Their Children's Schools: Barriers and Recommendations for Improvement

African Refugee Parents' Involvement in Their Children's Schools: Barriers and Recommendations for Improvement

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Date: December 2009
Creator: Githembe, Purity Kanini
Description: The purpose of this study was to examine involvement of African refugee parents in the education of their elementary school children. The setting of the study was Northern and Southern Texas. African refugee parents and their children's teachers completed written surveys and also participated in interviews. In the study's mixed-method design, quantitative measures provided data about parent involvement at home, parent involvement at school, frequency of parent-teacher contact, quality of parent-teacher relationship, parent endorsement of children's schools, and barriers to parent involvement. Qualitative data from the open-ended questions provided data on barriers and strategies to improve involvement. Sixty-one African refugee parents responded to the survey and also participated in an in-depth face-to-face or telephone interview. Twenty teacher participants responded to an online survey. Quantitative data gathered from the parent and teacher surveys were analyzed using frequency distributions and analyses of variance. Qualitative data were analyzed by summarizing and sorting information into different categories using Weft QDA, an open-source qualitative analysis software. From these data, I identified barriers to African refugee parent involvement in their children's schools, as well as challenges that teachers face as they try to involve African refugee parents. Results of analyses of variance revealed statistically significant differences ...
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The Afro-British Slave Narrative: The Rhetoric of Freedom in the Kairos of Abolition

The Afro-British Slave Narrative: The Rhetoric of Freedom in the Kairos of Abolition

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Date: December 1999
Creator: Evans, Dennis F.
Description: The dissertation argues that the development of the British abolition movement was based on the abolitionists' perception that their actions were kairotic; they attempted to shape their own kairos by taking temporal events and reinterpreting them to construct a kairotic process that led to a perceived fulfillment: abolition. Thus, the dissertation examines the rhetorical strategies used by white abolitionists to construct an abolitionist kairos that was designed to produce salvation for white Britons more than it was to help free blacks. The dissertation especially examines the three major texts produced by black persons living in England during the late eighteenth centuryIgnatius Sancho's Letters of the Late Ignatius Sancho (1782), Ottobauh Cugoano's Thoughts and Sentiments on the Evil of Slavery (1787), and Olaudah Equiano's The Interesting Narrative of the Life of Olaudah Equiano, or Gustavus Vassa, the African (1789)to illustrate how black rhetoric was appropriated by whites to fulfill their own kairotic desires. By examining the rhetorical strategies employed in both white and black rhetorics, the dissertation illustrates how the abolitionists thought the movement was shaped by, and how they were shaping the movement through, kairotic time. While the dissertation contends that the abolition movement was rhetorically designed to provide redemption, ...
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Alexander Johnson's Ni' Concerto (1994) - Concerto no. 1 for Piano and Orchestra: a Discussion of Influences from Africa, Eastern and Western Europe

Alexander Johnson's Ni' Concerto (1994) - Concerto no. 1 for Piano and Orchestra: a Discussion of Influences from Africa, Eastern and Western Europe

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Date: August 2001
Creator: Malan, Petronel
Description: In the new generation of artists emerging in South Africa, Alexander Johnson is considered the most prolific young composer of his day. In a recent review in the Pretoria News, Johnson has been praised by eminent critic Paul Boekkooi as a composer who has “an ear for the exotic and knows exactly how to bring it off....” He continued by noting that his music is “mentally engrossing, pleasurable to the senses and seems refreshingly free from dogmatic formulas." Johnson writes for musicians and the general public to equal satisfaction. His accessible compositions and catching use of melodic materials have made his writings very popular both in South Africa and abroad. During his residency in Belgrade in 1993-94, Johnson met Croatian pianist Dorian Leljak. Impressed with Johnson's compositional ideas and output, Leljak commissioned a work from Johnson for piano and orchestra. The result was the Niš Concerto, which Johnson completed in April 1994. The world premiere took place on June 23, 1994 with the Niš Philharmonic Orchestra conducted by Anatoli Nowiestski with Dorian Leljak as soloist. The Niš Concerto received its South African premiere in 1995 during a simultaneous celebration for “Europe Day” and the new democracy of the Republic of ...
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