Virulence Factor Production in PyrE Mutants of Pseudomonas Aeruginosa
Description:
It has been shown previously in our lab that mutations in the pyrimidine pathway reduced the ability of Pseudomonas aeruginosa to produce virulence factors. Knockout mutations in pyrB, pyrC and pyrD genes of the pyrimidine pathway showed that virulence factor production was decreased. Pyoverdin, pyocyanin, hemolysin, iron chelation, motility, and adherence are all considered virulence factors. Here I further investigate the effects of mutations in the pyrimidine pathway by studying a pyrE mutan…
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Date:
May 2010
Creator:
Niazy, Abdurahman
Partner:
UNT Libraries