Description: This thesis describes two experiments: one related to antihistamines, and the other related to antitubercular compounds.

Description: The Semiconductor Industry Association (SIA) has identified the integration of copper (Cu) with low-dielectric-constant (low-k) materials as a critical goal for future interconnect architectures. A fundamental understanding of the chemical interaction of Cu with various substrates, including diffusion barriers and adhesion promoters, is essential to achieve this goal. The objective of this research is to develop novel organic polymers as Cu/low-k interfacial layers and to investigate popular barrier candidates, such as clean and modified tantalum (Ta) substrates. Carbon-silicon (C-Si) polymeric films have been formed by electron beam bombardment or ultraviolet (UV) radiation of molecularly adsorbed vinyl silane precursors on metal substrates under ultra-high vacuum (UHV) conditions. Temperature programmed desorption (TPD) studies show that polymerization is via the vinyl groups, while Auger electron spectroscopy (AES) results show that the polymerized films have compositions similar to the precursors. Films derived from vinyltrimethyl silane (VTMS) are adherent and stable on Ta substrates until 1100 K. Diffusion of deposited Cu overlayers is not observed below 800 K, with dewetting occurred only above 400 K. Hexafluorobenzene moieties can also be incorporated into the growing film with good thermal stability. Studies on the Ta substrates demonstrate that even sub-monolayer coverages of oxygen or carbide on polycrystalline ...

Description: The purpose of this investigation is to reveal the effects of certain factors affecting adsorption on some specific precipitates. It is hoped that the choice of precipitate types will enable extension of the information gained here to other precipitates similar to those investigated.

Description: This thesis describes the synthesis of a series of dialkylaminoalkoxy derivatives of methyl p-nitrophenylacetate for testing as anti-histamine or hay fever drugs.

Description: In view of the increasing importance of thiophene derivatives as chemotherapeutic agents, it was considered of interest to apply the Reformatsky reaction to the synthesis of compounds containing the thiophene nucleus with the thought that these might serve as intermediates for further syntheses.