Colchicine Reversibly Inhibits Electrical Activity in Arthropod Mechanoreceptors
Description:
Dendrites of cockroach tibial spine mechanoreceptors contain hundreds of free microtubules, which may have some relation to the generation of electrical activity. Deflection of a spine produces a train of action potentials. Continuous perfusion over a period of 4 hours results in no response decrement. Perfusion with 10mM colchicine reversibly inhibits the response within 5-7 minutes. Irreversible inhibition is produced by perfusion with 1mM vinblastine sulfate in perfusion solution containing …
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Date:
August 1977
Creator:
Reagan, Paul D.
Partner:
UNT Libraries