UNT Theses and Dissertations - 421 Matching Results

Search Results

prev Results: 191 - 214 next
open access

Hematological Parameters of the Bluegill, Lepomis machrochirus (Rafinesque), Including Effects of Turbidity, Chloramines, and Flexibacter columnaris

Description: Normal ranges of values for hematological parameters of bluegill gathered seasonally from three lakes were determined. Sexual, seasonal, and inter-lake variations were found. Effects of 2-wk exposure to turbidity on blood parameters included an increase in rbc size and a decrease in small lymphocytes. Effects of 3-hr exposure were increases in rbc count, hemoglobin, and pH and decreases in PG2 and large lymphocytes. The effects of 0.44 and 0.88 ppm chloramines were an increase in blood pH, a de… more
Date: May 1976
Creator: Jones, Betty Juanelle
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

A High-fat Meal Alters Post-prandial mRNA Expression of SIRT1, SIRT4, and SIRT6

Description: Sirtuins (SIRT) regulate the transcription of various genes involved in the development of diet-induced obesity and chronic disease; however, it is unknown how they change acutely following a high-fat meal. The purpose of this study was to determine the effect of a high-fat meal (65% kcals/d; 85% fat recommendation), on SIRT1-7 mRNA expression in blood leukocytes at 1, 3, and 5-h post-prandial. Men and women (N=24) reported to the lab following an overnight fast (>12H). Total RNA was isolated a… more
Date: December 2015
Creator: Best Sampson, Jill Nicole
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Histochemical Characterization of Lymphocytes in Preleukemic and Leukemic AKR Mice

Description: The AKR strain of mice have a genetic trait for spontaneous development of lymphocytic leukemia. In this study, leukemic mice were found to have significantly larger (p<0.01) thymuses and spleens than preleukemic mice. The enlarged leukemic tissues were densely packed with a light staining cell, with a hollow-appearing nucleus. Tissues from preleukemic mice were observed to be infiltrated with a smaller, darker-staining lymphocyte. Fluorescent antibody staining was done on preleukemic and leuke… more
Date: May 1979
Creator: Michnoff, Carolyn A.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Histological age estimation of the midshaft clavicle using a new digital technique.

Description: Histological methods to estimate skeletal age at death, in forensic cases, are an alternative to the more traditional gross morphological methods. Most histological methods utilize counts of bone type within a given field for their estimation. The method presented in this paper uses the percentage area occupied by unremodeled bone to estimate age. The percentage area occupied by unremodeled bone is used in a linear regression model to predict skeletal age at death. Additionally, this method use… more
Date: August 2004
Creator: Ingraham, Mark R.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Home range analysis of rehabilitated and released great horned owls (Bubo virginianus) in Denton County, Texas, through radio telemetry.

Description: Raptor rehabilitation has become commonplace globally, yet studies on the survival and adaptation of great horned owls (Bubo virginianus) after release has been neglected to an appreciable extent. The primary objective of this study is to provide quantitative data on the success of rehabilitated and released great horned owls in the North Texas region. Owls (N=12) were rehabilitated and released onto the Ray Roberts Greenbelt Corridor in Denton County, Texas, and monitored using radio telemetry… more
Date: December 2007
Creator: Johnston, Jennifer Lynn
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Hypoxia and the Development of Endothermic Capacity in Chickens (Gallus Gallus)

Description: Adult chickens employ endothermy – internal generation of heat that maintains a constant body temperature (Tb). Prior to hatching, chicken embryos are ectothermic - controlling Tb by external heat sources. Upon hatching, the hatchling transitions from an ectotherm to an endotherm that has been shown to be delayed by hypoxia. In this study, whole animal oxygen consumption () and liver, heart, and skeletal muscle citrate synthase activity (CSA) and were measured during this transition to endothe… more
Date: August 2012
Creator: Neely, Aaron Mackallan
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Hypoxia-Induced Cardiac Arrest Alters Central Nervous System Concentrations of the GLYT2 Glycine Transporter in Zebrafish (Danio rerio)

Description: Hypoxia as a stressor has physiological implications that have been a focal point for many physiological studies in recent years. In some studies, hypoxia had large effects on the organ tissue degeneration, which ultimately effects multiple ecological processes. These organ tissue studies played a part in the development of new fields like neurocardiology, a specialty that studied the relationship between the brain and the heart. This thesis focuses on how hypoxia-induced cardiac arrest alte… more
Date: July 2023
Creator: Auzenne, Alexis
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Hypoxic and hyperoxic incubation affects the ductus arteriosus in the developing chicken embryo (Gallus gallus).

Description: Developing chicken embryos have two ductus arteriosus (DA) that shunt blood away from the lungs and to the chorioallantoic membrane, the embryonic gas exchanger. In mammals, DA closure is stimulated by an increase in blood gas O2 that occurs as the animal begins to breathe with its lungs. The goal of this study was to determine the influence of O2 levels during incubation on the vascular reactivity and morphology of the O2-sensitive DA and to examine the effects of changing O2 levels during l… more
Date: December 2009
Creator: Copeland, Jennifer
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Identification and Characterization of the Pyrimidine Biosynthetic Operon in Streptomyces griseus

Description: To further understand the ATCase/DHOase bifunctional complex formed in Streptomyces, the genes encoding these and other pyrimidine enzymes were identified and characterized. Polymerase chain reaction (PCR) was utilized in this effort. Primers were constructed by selecting conserved regions of pyrimidine genes from known gene and protein sequences of a wide variety of organisms. These sequences were then optimized to Streptomyces codon usage. PCR products were obtained from internal sites within… more
Date: May 1998
Creator: Hooten, Jody J. (Jody Jeran)
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Identification of Glycine as the Factor in Peptone Which Induces Pleomorphism in Azotobacter Vinelandii

Description: The rigid peptidoglycan layer of the cell wall is responsible for maintaining the structural integrity of bacteria. Antibiotics such as penicillin exert their anti-bacterial effect by inhibiting synthesis of peptodoglycan, and enzymes such as lysozyme destroy cell integrity by hydrolyzing specific bonds in the interior of this macromolecule. Defective cells can no longer withstand the high turgor pressure within the cell because they are no longer protected by a rigid wall and tend to become fr… more
Date: December 1972
Creator: Rosenthal, Raoul Simon
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Identification of the Neurobiological Basis of Hemodynamic Responses Correlated with Cognitive Stroop Task Performance After an Acute Bout of Aerobic Exercise

Description: Cardiovascular activities may increase the brain blood flow improving neuronal activities leading to improved cognition. Consequently, the effects of an acute bout of moderate intensity aerobic exercise on brain hemodynamics and its correlation with cognitive color-word Stroop task performance were tested. The Stroop tasks were congruent (color matches word) and incongruent (color does not match word). Prefrontal (PFC) and motor cortex (MC) blood flow was recorded by fNIRS (functional near-infr… more
Date: May 2018
Creator: Pal, Amrita
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Immunocompetence in the AKR Mouse

Description: A model for the study of the relationship of immunity to cancer is found in AKR mice which harbor Gross virus. This genetically transmitted virus is present in a latent form for months before it spontaneously induces leukemia. Many investigators have demonstrated near normal humoral responses, but abnormal cellular immunity in the preleukemic animal. With increasing age, pathology of the disease is expressed, reflecting diminished immunity. In this study, the ontogeny of humoral antibodies of A… more
Date: August 1976
Creator: Dunton, Helen
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Immunohistochemical characterization of neuronal cilia in the rat central nervous system.

Description: An anti-G"11 antibody was used to label neuronal cilia throughout the rat central nervous system. Immunoreactive cilia were observed in every examined region of the rat CNS, but not in monkey or mouse tissue. Antibodies to G"q and G"q/11 failed to label cilia. Immunoreactive cilia were observed as early as postnatal day 0 in spinal tissue, and postnatal day 3 in hypothalamic tissue. There was a statistically significant negative correlation between a region's mean cilium length and that region… more
Date: May 2002
Creator: Hughes, Rhome
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Immunohistochemistry of the Gills of the Channel Catfish Ictalurus Punctatus: Cells and Neurochemicals That May Be Involved in the Control of Cardioventilatory Reflexes

Description: In teleost fishes the neurochemicals involved in sensing and responding to hypoxia are unresolved. Serotonergic branchial neuroepithelial cells (NECs) are putative O2 chemoreceptors believed to be homologous to the neural crest (NC) derived APUD (amine-precursor uptake and decarboxylation) pulmonary NECs and carotid body type-1 glomus cells. Branchial NECs contain serotonin (5-HT), thought to be central to the induction of the hypoxic cardioventilatory reflexes. However, application of 5-HT … more
Date: December 2013
Creator: Oden, David S.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

An Immunological Study of Adults with Down Syndrome

Description: The high susceptibility to infection in persons with Down Syndrome (DS) has led some investigators to explore the possibility of a defect in the immune system. Studies to date indicate no defect in humoral immunity suggesting that the defect might be in the cellular immune functions, but no specific defect has been found. Our investigation of the cellular immune system of adult DS patients was conducted by examining (1) the number and function of T-lymphocytes, (2) the phagocytic function of gr… more
Date: August 1983
Creator: White, Olivia Masih
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Immunotoxicity of Chromium Contaminated Soil in the Earthworm, Lumbricus Terrestris

Description: Objective was to assess the toxicity of chromium (Cr) contaminated soil (CS) using the earthworm Lumbricus terrestris. Specific aims were to determine: (1) survival (LC50); .(2) immunotoxicity as indicated by lysozyme activity, coelomocyte counts, secretory (SR) and erythrocyte rosette (ER) formation, and phagocytosis; and (3) compare effects of CS exposure with those of Cr spiked artificial soil (AS) . CS Cr concentration was 8.78 mg/g with 98.2% being Cr^3+ and 1.8% being Cr^6+. Using 14 d AS… more
Date: May 1993
Creator: Mohammadian, Gholamreza
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

The Impact of Invasive Salmonids on Ecosystem Functioning in South America's Sub-Antarctic Inland and Marine Waters

Description: Invasions from coho salmon were first reported in the Cape Horn Biosphere Reserve (CHBR) in 2019 which is the most southern distribution registered to date. The CHBR is known for its high number of endemic species and unique biodiversity, such as the native fishes Galaxias maculatus and Aplochiton taeniatus. There are now three invasive salmonid species in the rivers of CHBR and are a potential threat to the native fish taxa. Stable isotope and gut content analysis were used to understand resou… more
This item is restricted from view until June 1, 2025.
Date: May 2023
Creator: Moore, Sabrina
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Implications of Diet in Cardiovascular Disease Risk: Postprandial Changes in Circulating Monocytes and Endotoxemia

Description: It is well established that continual consumption of a diet high in fat leads to the development of chronic conditions such as obesity, cardio metabolic syndrome, and atherosclerosis that are associated with high incidence of cardiovascular disease. Recent studies have identified endotoxin-derived inflammation as a major diving force for the development of these conditions. Our laboratory has recently demonstrated that consumption of a single high-fat meal results in acute postprandial endotoxe… more
Date: August 2018
Creator: Venable, Andrea Henning
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Improved Fabrication and Quality Control of Substrate Integrated Microelectrode Arrays

Description: Spontaneously active monolayer neuronal networks cultured on photoetched multimicroelectrode plates (MMEPs) offer great potential for use in studying neuronal networks. However, there are many problems associated with frequent, long-term use of MMEPs. The major problems include (1) polysiloxane insulation deterioration and breakdown, (2) and loss of gold at the gold electroplated indium-tin oxide (ITO) electrodes. The objective of this investigation was to correct these major problems. Qual… more
Date: May 2000
Creator: Zim, Bret E.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Improving Processing Efficiency for Forensic DNA Samples

Description: The goal of this project was to reduce processing time for forensic DNA testing without incurring significant added costs and/or the need for new instrumentation, while still generating high quality profiles. This was accomplished by: 1) extraction normalization using the ChargeSwitch® Forensic DNA Purification Kit such that a small range of DNA concentrations was consistently obtained, eliminating the need for sample quantification and dilution; 2) developing fast PCR protocols for STR primer … more
Date: May 2015
Creator: Connon, Catherine Cupples
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

In vitro Cultures of Morus alba for Enhancing Production of Phytoestrogens

Description: Plant estrogens have long been associated with health benefits. The potential of tissue culture techniques for the production of several secondary metabolites has been known for many years. Tissue cultures stimulate the production or induce the biosynthesis of novel compounds not found in the mature plant. Tissue culture of Morus alba, family Moraceae, is known to contain phytoestrogens, was established on plant-hormone supplemented Murashige and Skoog (MS) medium. Petiole and the stem tissue f… more
Date: December 2009
Creator: Bakshi, Vibhu
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

In Vitro Exploration of Functional Acrolein Toxicity with Cortical Neuronal Networks

Description: Acrolein is produced endogenously after traumatic brain injury (TBI) and is considered a primary mechanism for secondary damage occurring after TBI. We are using frontal cortex networks derived from mouse embryos and grown on microelectrode arrays in vitro to monitor the spontaneous activity of networks and the changes that occur after acrolein application. Networks exposed to acrolein exhibit a biphasic response profile. An initial increase in network activity, followed by a decrease to 100% a… more
Date: May 2018
Creator: Durant, Stormy R.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

In Vitro Investigations of Antibiotic Influences on Nerve Cell Network Responses to Pharmacological Agents

Description: Neuronal networks, derived from mouse embryonic frontal cortex (FC) tissue grown on microelectrode arrays, were used to investigate effects of gentamicin pretreatment on pharmacological response to the L-type calcium channel blocker, verapamil. Gentamicin is a broad spectrum antibiotic used to control bacterial contamination in cell culture. The addition of gentamicin directly to medium affects the pharmacological and morphological properties of the cells in culture. A reproducible dose respons… more
Date: December 2014
Creator: Sawant, Meera
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

In Vivo and In Vitro Transformations of Mouse Tissues from a Murine Lymphosarcoma

Description: The problem with which this investigation is concerned is that of determining the nature of events leading to the change. of normal cells into malignant cells. The design of the study is multi-phasic: (A) to establish the presence or absence of an oncogenic virion, (B) to demonstrate by use of the electron microscopy any ultracellular alteration in malignant or transformed tissues, (C) to investigate the nature of the transforming agent in the murine lymphosarcoma, and (D) to employ various met… more
Date: August 1972
Creator: Carnes, James Edgar
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
Back to Top of Screen