Characteristic Male Urine Microbiomes Associate with Asymptomatic Sexually Transmitted Infection

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Article discussing research on characteristic male urine microbiomes associated with asymptomatic sexually transmitted infection.

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7 p.

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Nelson, David E.; Van Der Pol, Barbara; Dong, Qunfeng; Revanna, Kashi V.; Fan, Baochang; Easwaran, Shraddha et al. November 2010.

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Article discussing research on characteristic male urine microbiomes associated with asymptomatic sexually transmitted infection.

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7 p.

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Abstract: Background: The microbiome of the male urogenital tract is poorly described but it has been suggested that bacterial colonization of the male urethra might impact risk of sexually transmitted infection (STI). Previous cultivation-dependent studies showed that a variety of non-pathogenic bacteria colonize the urethra but did not thoroughly characterize these microbiomes or establish links between the compositions of urethral microbiomes and STI. Methodology/Findings: Here, the authors used 165 rRNA PCR and sequencing to identify bacteria in urine specimens collected from men who lacked symptoms of urethral inflammation but who differed in status for STI. All of the urine samples contained multiple bacteria genera and many contained taxa that colonize the human vagina. Uncultivated bacteria associated with female genital tract pathology were abundant in specimens from men who had STI. Conclusions: Urine microbiomes from men with STI were dominated by fastidious, anaerobic and uncultivated bacteria. The same taxa were rare in STI negative individuals. The authors' findings suggest that the composition of male urine microbiomes is related to STI.

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  • PLoS One, 2010, San Francisco: Public Library of Science

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  • Publication Title: PLoS One
  • Volume: 5
  • Issue: 11
  • Pages: 7
  • Peer Reviewed: Yes

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UNT Scholarly Works

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  • November 2010

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  • April 2, 2012, 4:46 p.m.

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  • Aug. 12, 2020, 4:47 p.m.

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Nelson, David E.; Van Der Pol, Barbara; Dong, Qunfeng; Revanna, Kashi V.; Fan, Baochang; Easwaran, Shraddha et al. Characteristic Male Urine Microbiomes Associate with Asymptomatic Sexually Transmitted Infection, article, November 2010; [San Francisco, California]. (https://digital.library.unt.edu/ark:/67531/metadc78333/: accessed March 19, 2024), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; crediting UNT College of Arts and Sciences.

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