Amygdala involvement in human avoidance, escape and approach behavior

Description:

Article on amygdala involvement in human avoidance, escape and approach behavior. The authors examine amygdala reactivity to threatening cues when avoidance responding consistently prevented contact with an upcoming aversive event (money loss).

Creator(s):
Creation Date: November 1, 2010
Partner(s):
UNT College of Public Affairs and Community Service
Collection(s):
UNT Scholarly Works
Usage:
Total Uses: 115
Past 30 days: 8
Yesterday: 1
Creator (Author):
Schlund, Michael W.

University of North Texas; Kennedy Krieger Institute (Baltimore, Md.), Johns Hopkins University

Creator (Author):
Cataldo, Michael F.

Kennedy Krieger Institute (Baltimore, Md.), Johns Hopkins University

Publisher Info:
Publisher Name: Elsevier Science Ltd.
Place of Publication: [Amsterdam, Netherlands]
Date(s):
  • Creation: November 1, 2010
Description:

Article on amygdala involvement in human avoidance, escape and approach behavior. The authors examine amygdala reactivity to threatening cues when avoidance responding consistently prevented contact with an upcoming aversive event (money loss).

Degree:
Department: Behavior Analysis
Note:

Reprinted from Neuroimage, 53/2, Michael W. Schlund, Michael F. Cataldo, Amygdala involvement in human avoidance, escape and approach behavior, pp. 769-776, 2010, with permission from Elsevier Science Ltd. http://www.sciencedirect.com/science/article/pii/S105381191000916X

Note:

Abstract: Many forms of psychopathology and substance abuse problems are characterized by chronic ritualized forms of avoidance and escape behavior that are designed to control or modify external or internal (i.e., thoughts, emotions, bodily sensations) threats. In this functional magnetic resonance imaging investigation, the authors examined amygdala reactivity to threatening cues when avoidance responding consistently prevented contact with an upcoming aversive event (money loss). In addition, the authors examined escape responding that terminated immediate escalating money loss and approach responding that produced a future money gain. Results showed cues prompting avoidance, escape and approach behavior recruited a similar fronto-striatal-parietal network. Within the amygdala, bilateral activation was observed to threatening avoidance and escape cues, even though money loss was consistently avoided, as well as to the reward cue. The magnitude of amygdala responses within-subjects was relatively similar to avoidance, escape and approach cues, but considerable between-subject differences were found. The heightened amygdala response to avoidance and escape cues observed within a subset of subjects suggests threat related responses can be maintained even when aversive events are consistently avoided, which may account for the persistence of avoiding-coping in various clinical disorders. Further assessment of the relation between amygdala reactivity and avoidance-escape behavior may prove useful in identifying individuals with or at risk for neuropsychiatric disorders.

Physical Description:

16 p.

Language(s):
Subject(s):
Keyword(s): approaches | avoidance | escapes | amydala | rewards | anxiety
Source: Neuroimage, 2010, Amsterdam: Elsevier Science Ltd., pp. 769-776
Partner:
UNT College of Public Affairs and Community Service
Collection:
UNT Scholarly Works
Identifier:
  • DOI: 10.1016/j.neuroimage.2010.06.058
  • ARK: ark:/67531/metadc77178
Resource Type: Article
Format: Text
Rights:
Access: Public
Citation:
Publication Title: Neuroimage
Volume: 53
Issue: 2
Page Start: 769
Page End: 776
Peer Reviewed: Yes