Multinetwork Nerve Cell Assay Platform with Parallel Recording Capability

Description:

Patent relating to a multinetwork nerve cell assay platform with parallel recording capability.

Creator(s): Gross, Guenter W.
Location(s): United States - Texas - Denton County - Denton
Creation Date: June 11, 2013
Partner(s):
UNT College of Arts and Sciences
Collection(s):
UNT Scholarly Works
Usage:
Total Uses: 3
Past 30 days: 0
Yesterday: 0
Creator (Inventor):
Gross, Guenter W.

University of North Texas

Publisher Info:
Place of Publication: [Washington, D.C.]
Date(s):
  • Submitted: September 12, 2007
  • Accepted: June 11, 2013
  • Creation: June 11, 2013
Coverage:
Place
United States - Texas - Denton County - Denton
Description:

Patent relating to a multinetwork nerve cell assay platform with parallel recording capability.

Degree:
Department: Biological Sciences
Note:

Abstract: A neuronal network analysis plate having alternating rows of recording wells and amplifying wells. The recording wells contain a neural cell network and a series of electrodes for recording the action potential signals of the neurons. The electrodes are connected to amplifiers in adjacent amplifying wells. The close proximity of these amplifiers ideal because it permits the parallel, non-multiplexed recording of action potential signals from multiple different active nerve cell networks. The amplifiers in the amplifying wells can then be connected to external amplification equipment. The neuronal network analysis plate may be contained within a single commercially available 24 or 96 well plate. The neuronal network analysis plate can be used to detect and quantify pharmacological and toxicological responses of the neural cells to one or more agents in vitro.

Note:

Prior Publication Data: US 2009/0291466 A1, November 26, 2009.

Note:

Related U.S. Application Data: Provisional application number 60/845399, filed on September 18, 2006.

Physical Description:

9 p. : ill.

Language(s):
Subject(s):
Keyword(s): neuronal networks | cell cultures | parallel recording
Contributor(s):
Partner:
UNT College of Arts and Sciences
Collection:
UNT Scholarly Works
Identifier:
  • PAT-NO: 8460921
  • GOVNO: 12/441703
  • GOVNO: PCT/US2007/019780
  • ARK: ark:/67531/metadc306940
Resource Type: Patent
Format: Text
Rights:
Access: Public