The UNT College of Arts and Sciences educates students in traditional liberal arts, performing arts, sciences, professional, and technical academic programs. In addition to its departments, the college includes academic centers, institutes, programs, and offices providing diverse courses of study.
Article on the solubility of clonazepam, diazepam, lamotrigine, and phenobarbital in N-methyl-2-pyrrolidone + water mixtures at 298.2 K.
Physical Description
3 p.
Notes
Abstract: Experimental solubilities of clonazepam, diazepam, lamotrigine, and phenobarbital in binary solvent mixtures of N-methyl-2-pyrrolidone (NMP) + water at 298.2 K were reported. The solubility of clonazepam, diazepam, and lamotrigine was increased with the addition of NMP, and maximum values are in neat NMP. The solubility of phenobarbital was increased with addition of NMP, reached the maximum value, and then decreased with further increase in NMP concentration. The Jouyban−Acree model was fitted to the results of these measurements, and solubilities were back-calculated by employing the solubility data in monosolvents in which the overall mean deviation of the models was 10.7 %.
Reprinted with permission from the Journal of Chemical and Engineering Data. Copyright 2009 American Chemical Society.
Publication Title:
Journal of Chemical and Engineering Data
Volume:
54
Issue:
10
Page Start:
2964
Page End:
2966
Peer Reviewed:
Yes
Collections
This article is part of the following collection of related materials.
UNT Scholarly Works
Materials from the UNT community's research, creative, and scholarly activities and UNT's Open Access Repository. Access to some items in this collection may be restricted.
Shayanfar, Ali; Acree, William E. (William Eugene) & Jouyban, Abolghasem.Solubility of Clonazepam, Diazepam, Lamotrigine, and Phenobarbital in N-Methyl-2-pyrrolidone + Water Mixtures at 298.2 K,
article,
June 4, 2009;
[Washington, D.C.].
(https://digital.library.unt.edu/ark:/67531/metadc303228/:
accessed April 25, 2024),
University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu;
crediting UNT College of Arts and Sciences.
