On the Solubility of Quercetin

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Article discussing the solubility of quercetin. The authors have applied a methodology based on linear free energy equations for water-solvent and gas-solvent partitions to study solubilities.

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8 p.

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Abraham, M. H. (Michael H.) & Acree, William E. (William Eugene) May 15, 2014.

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Article discussing the solubility of quercetin. The authors have applied a methodology based on linear free energy equations for water-solvent and gas-solvent partitions to study solubilities.

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8 p.

Notes

Abstract: There is a considerable disagreement over the solubility of quercetin in water. Experimental values of log Cw with Cw in mol/L range from − 2.52 to − 5.89, a difference of over three log units. We have applied a methodology based on linear free energy equations for water-solvent and gas-solvent partitions to study solubilities. These are related to partition coefficients through Ps = Cs/Cw where Cs and Cw are solubilities of a given solute in a solvent and in water. We find that known solubilities of quercetin in methanol and ethanol at 298 K and a known water-solvent partition coefficient can be accommodated in the same model if the water solubility at 298 K, as log Cw, is taken as − 3.90, that is near to the middle of the range of experimental values. Our model successfully predicts solubilities of quercetin in water–ethanol mixtures near to the ethanol rich mixtures.

This is the accepted manuscript version of the article. Reprinted with permission from Elsevier Science Ltd., all rights reserved. The final definitive version is available here: http://dx.doi.org/10.1016/j.molliq.2014.05.006

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  • Journal of Molecular Liquids, 197, Elsevier Science Ltd., May 15, 2014, pp. 1-8

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  • Publication Title: Journal of Molecular Liquids
  • Volume: 197
  • Page Start: 157
  • Page End: 159
  • Peer Reviewed: Yes

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  • May 15, 2014

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  • May 29, 2014, 5:29 p.m.

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  • Dec. 8, 2023, 12:50 p.m.

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Abraham, M. H. (Michael H.) & Acree, William E. (William Eugene). On the Solubility of Quercetin, article, May 15, 2014; [New York, New York]. (https://digital.library.unt.edu/ark:/67531/metadc287064/: accessed March 19, 2024), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; crediting UNT College of Arts and Sciences.

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