The Effect of Steroid Dose Regimen on the Relationship Between Lower Extremity Muscle Function and Cardiac Function in Post Heart Transplant Patients

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Description:

Differences in cardiovascular/aerobic function in heart transplant patients might be attributed to the rate of corticosteroid withdrawal and/or to skeletal muscle function. This hypothesis was tested among nine male, cardiac transplant recipients. Prednisone dosage was monitored, and isokinetic strength testing was performed at 4 different time periods throughout the first year post-transplantation. Cardiovascular/aerobic measurements were obtained at the fourth time period. Pre-surgery characteristics were obtained from the patient's medical record. Significant Pearson-product moment correlations were only found between muscle function and aerobic function and between pre-surgery characteristics and cardiovascular/aerobic performance. The results of this study show no evidence that rapid reduction of prednisone dosage enhances aerobic function by benefiting skeletal muscle function.

Creator(s): Galatas, Mary V.
Creation Date: May 2001
Partner(s):
UNT Libraries
Collection(s):
UNT Theses and Dissertations
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Total Uses: 210
Past 30 days: 1
Yesterday: 0
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Publisher Info:
Publisher Name: University of North Texas
Place of Publication: Denton, Texas
Date(s):
  • Creation: May 2001
  • Digitized: July 17, 2007
Description:

Differences in cardiovascular/aerobic function in heart transplant patients might be attributed to the rate of corticosteroid withdrawal and/or to skeletal muscle function. This hypothesis was tested among nine male, cardiac transplant recipients. Prednisone dosage was monitored, and isokinetic strength testing was performed at 4 different time periods throughout the first year post-transplantation. Cardiovascular/aerobic measurements were obtained at the fourth time period. Pre-surgery characteristics were obtained from the patient's medical record. Significant Pearson-product moment correlations were only found between muscle function and aerobic function and between pre-surgery characteristics and cardiovascular/aerobic performance. The results of this study show no evidence that rapid reduction of prednisone dosage enhances aerobic function by benefiting skeletal muscle function.

Degree:
Level: Master's
Discipline: Kinesiology
Language(s):
Subject(s):
Keyword(s): prednisone | heart | transplantation | muscle | strength
Contributor(s):
Partner:
UNT Libraries
Collection:
UNT Theses and Dissertations
Identifier:
  • OCLC: 47833626 |
  • ARK: ark:/67531/metadc2761
Resource Type: Thesis or Dissertation
Format: Text
Rights:
Access: Use restricted to UNT Community
License: Copyright
Holder: Galatas, Mary V.
Statement: Copyright is held by the author, unless otherwise noted. All rights reserved.