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Article discussing the solubility of benzodiazepines in polyethylene glycol 200 plus water mixtures at 303.2 K.
Physical Description
4 p.
Notes
Reprinted with permission from the Journal of Chemical and Engineering Data. Copyright 2009 American Chemical Society.
Abstract: Experimental solubilities of chlordiazepoxide, diazepam, and lorazepam in polyethylene glycol 200 (PEG 200) + water mixtures at 303.2 K were reported. The solubility of each drug increased exponentially with the addition of PEG 200 and reached the maximum value in neat PEG 200. The Jouyban−Acree model was used to mathematically describe the experimental data, and the solubilities were predicted using a previously trained version of the Jouyban−Acree model for PEG + water mixtures and the solubility data in monosolvents. The overall mean relative deviations of the models were 3.7% and 18.3%, respectively, for the fitted model and the trained version.
Publication Title:
Journal of Chemical and Engineering Data
Volume:
55
Issue:
1
Page Start:
519
Page End:
522
Peer Reviewed:
Yes
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Jouyban, Abolghasem; Shokri, Javad; Barzegar-Jalali, Mohammad; Hassanzadeh, Davoud; Acree, William E. (William Eugene); Ghafourian, Taravat et al.Solubility of Benzodiazepines in Polyethylene Glycol 200 + Water Mixtures at 303.2 K,
article,
June 15, 2009;
[Washington, D.C.].
(https://digital.library.unt.edu/ark:/67531/metadc172356/:
accessed April 23, 2024),
University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu;
crediting UNT College of Arts and Sciences.
