Solubility of Benzodiazepines in Polyethylene Glycol 200 + Water Mixtures at 303.2 K

Description:

Article discussing the solubility of benzodiazepines in polyethylene glycol 200 plus water mixtures at 303.2 K.

Creator(s):
Creation Date: June 15, 2009
Partner(s):
UNT College of Arts and Sciences
Collection(s):
UNT Scholarly Works
Usage:
Total Uses: 116
Past 30 days: 0
Yesterday: 0
Creator (Author):
Jouyban, Abolghasem

Tabriz University of Medical Sciences

Creator (Author):
Shokri, Javad

Tabriz University of Medical Sciences

Creator (Author):
Barzegar-Jalali, Mohammad

Tabriz University of Medical Sciences

Creator (Author):
Hassanzadeh, Davoud

Tabriz University of Medical Sciences

Creator (Author):
Acree, William E. (William Eugene)

University of North Texas

Creator (Author):
Ghafourian, Taravat

Universities of Kent and Greenwich

Creator (Author):
Nokhodchi, Ali

Universities of Kent and Greenwich

Publisher Info:
Publisher Name: American Chemical Society
Place of Publication: [Washington, D.C.]
Date(s):
  • Creation: June 15, 2009
Description:

Article discussing the solubility of benzodiazepines in polyethylene glycol 200 plus water mixtures at 303.2 K.

Degree:
Department: Chemistry
Note:

Reprinted with permission from the Journal of Chemical and Engineering Data. Copyright 2009 American Chemical Society.

Note:

Abstract: Experimental solubilities of chlordiazepoxide, diazepam, and lorazepam in polyethylene glycol 200 (PEG 200) + water mixtures at 303.2 K were reported. The solubility of each drug increased exponentially with the addition of PEG 200 and reached the maximum value in neat PEG 200. The Jouyban−Acree model was used to mathematically describe the experimental data, and the solubilities were predicted using a previously trained version of the Jouyban−Acree model for PEG + water mixtures and the solubility data in monosolvents. The overall mean relative deviations of the models were 3.7% and 18.3%, respectively, for the fitted model and the trained version.

Physical Description:

4 p.

Language(s):
Subject(s):
Keyword(s): benzodiazepines | polyethylene glycol | chlordiazepoxide | diazepam
Source: Journal of Chemical and Engineering Data, 2009, Washington DC: American Chemical Society, pp. 519-522
Partner:
UNT College of Arts and Sciences
Collection:
UNT Scholarly Works
Identifier:
  • DOI: 10.1021/je90033p |
  • ARK: ark:/67531/metadc172356
Resource Type: Article
Format: Text
Rights:
Access: Public
Citation:
Publication Title: Journal of Chemical and Engineering Data
Volume: 55
Issue: 1
Page Start: 519
Page End: 522
Peer Reviewed: Yes